![]() The TYM-I showed the highest discrimination ability among individuals aged more than 70 and high educational level (AUC = 0.89). A TYM-I score lower or equal to 36 was found to be optimal cut off to detect MCI. TYM-I had a similar area under the curve (AUC = 0.85) point estimate as Mini Mental State Examination (MMSE) (AUC = 0.83). Receiver Operating Characteristic (ROC) analyses were conducted to find the optimal cut-off and measure discrimination ability of TYM-I in detecting MCI. ![]() An extended formal neuropsychological test battery was used to define MCI subtypes. The clinical diagnosis of MCI was considered as the gold standard. TYM-I was administered to 94 MCI patients and 134 healthy controls. We assessed the discrimination ability of the Italian version of the TYM (TYM-I) in detecting Mild Cognitive Impairment (MCI) in clinical setting. It requires minimal administrator supervision and the computation of the final test score takes approximately 2 min. The Test Your Memory (TYM) is a brief self-administered, cognitive screening test, currently used in several settings. 7Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari “Aldo Moro”, Bari, Italy.6Laboratory of Geriatric Neuropsychiatry, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.5UCL Huntington’s Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.4Clinical Psychology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ospedale Policlinico San Martino, Genoa, Italy.3Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Mother-Child health (DINOGMI), University of Genoa, Genova, Italy.2Institute of Public Health, Charité – Universitätsmedizin Berlin, Berlin, Germany.1Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari “Aldo Moro”, “Pia Fondazione Cardinale G.Maria Rosaria Barulli 1* Marco Piccininni 1,2 Andrea Brugnolo 3,4 Cinzia Musarò 1 Cristina Di Dio 1 Rosa Capozzo 1 Rosanna Tortelli 1,5 Ugo Lucca 6 Giancarlo Logroscino 1,7
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